Herpes Simplex Virus Vectors Elicit Durable Immune Responses in the Presence of Preexisting Host Immunity

Herpes simplex virus (HSV) recombinants are being developed as vaccine vectors for the expression of heterologous antigens. There is concern, however, that preexisting HSV immunity may decrease their effectiveness. We have addressed this issue in an animal model. Immunized mice were inoculated with...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Brockman, Mark A., Knipe, David M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136066/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11907207/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.8.3678-3687.2002
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