Enhancing the Proteolytic Maturation of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins

In virus-infected cells, the envelope glycoprotein (Env) precursor, gp160, of human immunodeficiency virus type 1 is cleaved by cellular proteases into a fusion-competent gp120-gp41 heterodimer in which the two subunits are noncovalently associated. However, cleavage can be inefficient when recombin...

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Pubblicato in:	J Virol
Autori principali:	Binley, James M., Sanders, Rogier W., Master, Aditi, Cayanan, Charmagne S., Wiley, Cheryl L., Schiffner, Linnea, Travis, Bruce, Kuhmann, Shawn, Burton, Dennis R., Hu, Shiu-Lok, Olson, William C., Moore, John P.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Vaccines and Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135977/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.6.2606-2616.2002
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