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Cooperative subunit interactions within the oligomeric envelope glycoprotein of HIV-1: Functional complementation of specific defects in gp120 and gp41

The envelope glycoprotein (Env) of HIV-1 is displayed on the surface of the virion or infected cell as an oligomer of multiple gp120/gp41 complexes. We sought to unravel the relationships between this oligomeric structure and the requirements for sequential interactions with CD4 and coreceptor (CCR5...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Salzwedel, Karl, Berger, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2000
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18843/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050186/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.230438497
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