Probing the Sialic Acid Binding Site of the Hemagglutinin-Neuraminidase of Newcastle Disease Virus: Identification of Key Amino Acids Involved in Cell Binding, Catalysis, and Fusion

We recently reported the first crystal structure of a paramyxovirus hemagglutinin-neuraminidase (HN) from Newcastle disease virus. This multifunctional protein is responsible for binding to cellular sialyl-glycoconjugate receptors, promotion of fusion through interaction with the second viral surfac...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Connaris, Helen, Takimoto, Toru, Russell, Rupert, Crennell, Susan, Moustafa, Ibrahim, Portner, Allen, Taylor, Garry
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135884/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11799177/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.4.1816-1824.2002
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