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Probing the Sialic Acid Binding Site of the Hemagglutinin-Neuraminidase of Newcastle Disease Virus: Identification of Key Amino Acids Involved in Cell Binding, Catalysis, and Fusion

We recently reported the first crystal structure of a paramyxovirus hemagglutinin-neuraminidase (HN) from Newcastle disease virus. This multifunctional protein is responsible for binding to cellular sialyl-glycoconjugate receptors, promotion of fusion through interaction with the second viral surfac...

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書誌詳細
出版年:J Virol
主要な著者: Connaris, Helen, Takimoto, Toru, Russell, Rupert, Crennell, Susan, Moustafa, Ibrahim, Portner, Allen, Taylor, Garry
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135884/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11799177/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.4.1816-1824.2002
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