Highly conserved modified nucleosides influence Mg(2+)-dependent tRNA folding

Transfer RNA structure involves complex folding interactions of the TΨC domain with the D domain. However, the role of the highly conserved nucleoside modifications in the TΨC domain, rT(54), Ψ(55) and m(5)C(49), in tertiary folding is not understood. To determine whether these modified nucleosides...

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Bibliographic Details
Main Authors: Nobles, Kelly N., Yarian, Connie S., Liu, Guihua, Guenther, Richard H., Agris, Paul F.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC135809/
https://ncbi.nlm.nih.gov/pubmed/12409466
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