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Modified constructs of the tRNA TΨC domain to probe substrate conformational requirements of m(1)A(58) and m(5)U(54) tRNA methyltransferases
The TΨC stem and loop (TSL) of tRNA contains highly conserved nucleoside modifications, m(5)C(49), T(54), Ψ(55) and m(1)A(58). U(54) is methylated to m(5)U (T) by m(5)U(54) methyltransferase (RUMT); A(58) is methylated to m(1)A by m(1)A(58) tRNA methyltransferase (RAMT). RUMT recognizes and methylat...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC111031/ https://ncbi.nlm.nih.gov/pubmed/10684932 |
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