Alternate exon insertion controls selective ubiquitination and degradation of different AUF1 protein isoforms
The A+U-rich element (ARE) in the 3′ non-coding region (3′ NCR) of short-lived cytokine mRNAs binds several regulatory proteins, including hnRNP D/AUF1, which comprises four isoforms of 37, 40, 42 and 45 kDa. ARE-mRNA degradation involves ubiquitin–proteasome activity, and one or more AUF1 proteins...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135764/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12136087/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf444 |
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