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AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation

AU-rich elements (AREs, usually containing repeated copies of AUUUA), when present in the 3′-untranslated regions (UTRs) of many mammalian mRNAs, confer instability on their host RNA molecules. The viral small nuclear RNA (snRNA) Herpesvirus saimiri U RNA 1 (HSUR 1) also contains an AUUUA-rich seque...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Fan, Xinhao Cynthia, Myer, Vic E., Steitz, Joan A.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316563/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9334320/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.19.2557
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