AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation

AU-rich elements (AREs, usually containing repeated copies of AUUUA), when present in the 3′-untranslated regions (UTRs) of many mammalian mRNAs, confer instability on their host RNA molecules. The viral small nuclear RNA (snRNA) Herpesvirus saimiri U RNA 1 (HSUR 1) also contains an AUUUA-rich seque...

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Bibliographic Details
Main Authors: Fan, Xinhao Cynthia, Myer, Vic E., Steitz, Joan A.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1997
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC316563/
https://ncbi.nlm.nih.gov/pubmed/9334320
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