The Rapamycin-Binding Domain Governs Substrate Selectivity by the Mammalian Target of Rapamycin

The mammalian target of rapamycin (mTOR) is a Ser/Thr (S/T) protein kinase, which controls mRNA translation initiation by modulating phosphorylation of the translational regulators PHAS-I and p70(S6K). Here we show that in vitro mTOR is able to phosphorylate these two regulators at comparable rates....

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Mol Cell Biol
Autori principali:	McMahon, Lloyd P., Choi, Kin M., Lin, Tai-An, Abraham, Robert T., Lawrence, John C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2002
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12370290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.21.7428-7438.2002
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!