Loading...

The Rapamycin-Binding Domain Governs Substrate Selectivity by the Mammalian Target of Rapamycin

The mammalian target of rapamycin (mTOR) is a Ser/Thr (S/T) protein kinase, which controls mRNA translation initiation by modulating phosphorylation of the translational regulators PHAS-I and p70(S6K). Here we show that in vitro mTOR is able to phosphorylate these two regulators at comparable rates....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: McMahon, Lloyd P., Choi, Kin M., Lin, Tai-An, Abraham, Robert T., Lawrence, John C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC135667/
https://ncbi.nlm.nih.gov/pubmed/12370290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.21.7428-7438.2002
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!