Induction of Extracellular Matrix-Remodeling Genes by the Senescence-Associated Protein APA-1

Human fibroblasts undergo cellular senescence after a finite number of divisions, in response to the erosion of telomeres. In addition to being terminally arrested in the cell cycle, senescent fibroblasts express genes that are normally induced upon wounding, including genes that remodel the extrace...

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Bibliografski detalji
Glavni autori: Benanti, Jennifer A., Williams, Dawnnica K., Robinson, Kristin L., Ozer, Harvey L., Galloway, Denise A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Cell Growth and Development
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC135658/
https://ncbi.nlm.nih.gov/pubmed/12370286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.21.7385-7397.2002
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