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The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase β
Genome instability is a characteristic of cancer and aging, and is a hallmark of the premature aging disorder Werner syndrome (WS). Evidence suggests that the Werner syndrome protein (WRN) contributes to the maintenance of genome integrity through its involvement in DNA repair. In particular, bioche...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356534/ https://ncbi.nlm.nih.gov/pubmed/16449207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj475 |
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