MLL-AFX Requires the Transcriptional Effector Domains of AFX To Transform Myeloid Progenitors and Transdominantly Interfere with Forkhead Protein Function

MLL-AFX is a fusion gene created by t(X;11) chromosomal translocations in a subset of acute leukemias of either myeloid or lymphoid derivation. It codes for a chimeric protein consisting of MLL fused to AFX, a forkhead transcription factor that normally regulates genes involved in apoptosis and cell...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Mol Cell Biol
Päätekijät:	So, Chi Wai, Cleary, Michael L.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis 2002
Aiheet:	Transcriptional Regulation
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135648/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12192052/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.18.6542-6552.2002
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!