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Inhibition of cap-dependent translation via phosphorylation of eIF4G by protein kinase Pak2
Translation is downregulated in response to a variety of moderate stresses, including serum deprivation, hyperosmolarity and ionizing radiation. The cytostatic p21-activated protein kinase 2 (Pak2)/γ-PAK is activated under the same stress conditions. Expression of wild-type Pak2 in cells and additio...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356308/ https://ncbi.nlm.nih.gov/pubmed/16281055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600868 |
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