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Inhibition of cap-dependent translation via phosphorylation of eIF4G by protein kinase Pak2

Translation is downregulated in response to a variety of moderate stresses, including serum deprivation, hyperosmolarity and ionizing radiation. The cytostatic p21-activated protein kinase 2 (Pak2)/γ-PAK is activated under the same stress conditions. Expression of wild-type Pak2 in cells and additio...

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Sonraí Bibleagrafaíochta
Main Authors: Ling, Jun, Morley, Simon J, Traugh, Jolinda A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356308/
https://ncbi.nlm.nih.gov/pubmed/16281055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600868
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