Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation

Picornavirus proteases cleave translation initiation factor eIF4G into a C-terminal two-thirds fragment (hereafter named p100) and an N-terminal one-third fragment, which interacts with the cap-binding factor eIF4E. As the timing of this cleavage correlates broadly with the shut-off of host cell pro...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Ali, Iraj K., McKendrick, Linda, Morley, Simon J., Jackson, Richard J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149147/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.15.4233
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