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Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation
Picornavirus proteases cleave translation initiation factor eIF4G into a C-terminal two-thirds fragment (hereafter named p100) and an N-terminal one-third fragment, which interacts with the cap-binding factor eIF4E. As the timing of this cleavage correlates broadly with the shut-off of host cell pro...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149147/ https://ncbi.nlm.nih.gov/pubmed/11483526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4233 |
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