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Negative Control of the Myc Protein by the Stress-Responsive Kinase Pak2
Pak2 is a serine/threonine kinase that participates in the cellular response to stress. Among the potential substrates for Pak2 is the protein Myc, encoded by the proto-oncogene MYC. Here we demonstrate that Pak2 phosphorylates Myc at three sites (T358, S373, and T400) and affects Myc functions both...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC344192/ https://ncbi.nlm.nih.gov/pubmed/14749374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1582-1594.2004 |
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