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Negative Control of the Myc Protein by the Stress-Responsive Kinase Pak2

Pak2 is a serine/threonine kinase that participates in the cellular response to stress. Among the potential substrates for Pak2 is the protein Myc, encoded by the proto-oncogene MYC. Here we demonstrate that Pak2 phosphorylates Myc at three sites (T358, S373, and T400) and affects Myc functions both...

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Main Authors: Huang, Zhongdong, Traugh, Jolinda A., Bishop, J. Michael
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC344192/
https://ncbi.nlm.nih.gov/pubmed/14749374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1582-1594.2004
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