Fe(2+)-Tetracycline-Mediated Cleavage of the Tn10 Tetracycline Efflux Protein TetA Reveals a Substrate Binding Site near Glutamine 225 in Transmembrane Helix 7

TetA specified by Tn10 is a class B member of a group of related bacterial transport proteins of 12 transmembrane alpha helices that mediate resistance to the antibiotic tetracycline. A tetracycline-divalent metal cation complex is expelled from the cell in exchange for a entering proton. The site(s...

Celý popis

Podrobná bibliografie

Vydáno v:	J Bacteriol
Hlavní autoři:	McMurry, Laura M., Aldema-Ramos, Mila L., Levy, Stuart B.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Microbial Cell Biology
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135328/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12193628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.18.5113-5120.2002
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!