Decreased function of the class B tetracycline efflux protein Tet with mutations at aspartate 15, a putative intramembrane residue.

The aspartate 15 residue within the first predicted intramembrane helix of the tetracycline efflux protein Tet has been conserved in four tetracycline resistance determinants from gram-negative bacteria. Its replacement in class B Tet by tyrosine, histidine, or asparagine resulted in a 60 to 85% los...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	McMurry, L M, Stephan, M, Levy, S B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207700/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1328154/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.19.6294-6297.1992
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