Lack of Strand Bias in UV-Induced Mutagenesis in Escherichia coli

We have investigated whether UV-induced mutations are created with equal efficiency on the leading and lagging strands of DNA replication. We employed an assay system that permits measurement of mutagenesis in the lacZ gene in pairs of near-identical strains. Within each pair, the strains differ onl...

Full description

Saved in:
Bibliographic Details
Main Authors: Gawel, Damian, Maliszewska-Tkaczyk, Magdalena, Jonczyk, Piotr, Schaaper, Roel M., Fijalkowska, Iwona J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC135265/
https://ncbi.nlm.nih.gov/pubmed/12142415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.16.4449-4454.2002
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items