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Lack of Strand Bias in UV-Induced Mutagenesis in Escherichia coli

We have investigated whether UV-induced mutations are created with equal efficiency on the leading and lagging strands of DNA replication. We employed an assay system that permits measurement of mutagenesis in the lacZ gene in pairs of near-identical strains. Within each pair, the strains differ onl...

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Detalhes bibliográficos
Main Authors: Gawel, Damian, Maliszewska-Tkaczyk, Magdalena, Jonczyk, Piotr, Schaaper, Roel M., Fijalkowska, Iwona J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135265/
https://ncbi.nlm.nih.gov/pubmed/12142415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.16.4449-4454.2002
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