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Lack of Strand Bias in UV-Induced Mutagenesis in Escherichia coli

We have investigated whether UV-induced mutations are created with equal efficiency on the leading and lagging strands of DNA replication. We employed an assay system that permits measurement of mutagenesis in the lacZ gene in pairs of near-identical strains. Within each pair, the strains differ onl...

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Détails bibliographiques
Auteurs principaux: Gawel, Damian, Maliszewska-Tkaczyk, Magdalena, Jonczyk, Piotr, Schaaper, Roel M., Fijalkowska, Iwona J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC135265/
https://ncbi.nlm.nih.gov/pubmed/12142415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.16.4449-4454.2002
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