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Genetic deletion of the norepinephrine transporter decreases vulnerability to seizures

Norepinephrine (NE) has been reported to modulate neuronal excitability and act as endogenous anticonvulsant. In the present study we used NE transporter knock-out mice (NET-KO), which are characterized by high levels of extracellular NE, to investigate the role of endogenous NE in seizure susceptib...

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Detalhes bibliográficos
Main Authors: Kaminski, Rafal M., Shippenberg, Toni S., Witkin, Jeffrey M., Rocha, Beatriz A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352306/
https://ncbi.nlm.nih.gov/pubmed/15911120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2005.02.056
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