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Cytokines inhibit norepinephrine transporter expression by decreasing Hand2

Functional noradrenergic transmission requires the coordinate expression of enzymes involved in norepinephrine (NE) synthesis, as well as the norepinephrine transporter (NET) which removes NE from the synapse. Inflammatory cytokines acting through gp130 can suppress the noradrenergic phenotype in sy...

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Detalhes bibliográficos
Main Authors: Pellegrino, Michael J., Parrish, Diana C., Zigmond, Richard E., Habecker, Beth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046314/
https://ncbi.nlm.nih.gov/pubmed/21241805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2011.01.008
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