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Activation of c-Jun NH(2)-Terminal Kinase (JNK) Is Required for Gemcitabine’s Cytotoxic Effect in Human Lung Cancer H1299 Cells
Although gemcitabine is a potent therapeutic agent in the treatment of human non-small cell lung cancer (NSCLC), resistance to gemcitabine is common. In this study, we investigated the molecular mechanisms involved in acquired gemcitabine resistance against NSCLC cells. Gemcitabine-resistant NSCLC H...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1351098/ https://ncbi.nlm.nih.gov/pubmed/16307741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2005.10.064 |
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