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Identification of a novel synthetic thiazolidin compound capable of inducing c-Jun N-terminal kinase-dependent apoptosis in human colon cancer cells

Development of new therapeutic agents for colon cancer is highly desirable. To this end, we screened a chemical library for new anticancer agents and identified a synthetic compound, 5-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin (DBPT), that kills cancer cells more effectively than it...

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Detalhes bibliográficos
Main Authors: Teraishi, Fuminori, Wu, Shuhong, Zhang, Lidong, Guo, Wei, Davis, John J., Dong, Fengqin, Fang, Bingliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592468/
https://ncbi.nlm.nih.gov/pubmed/16024641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-0575
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