Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors

Proteasome inhibitors have emerged as promising anticancer therapeutic agents. Bortezomib (PS-341), a specific proteasome inhibitor, exhibits antitumor activity against a wide range of malignancies and has been approved by the U.S. Food and Drug Administration for the treatment of relapsed or refrac...

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Detalhes bibliográficos
Main Authors: Zhu, Hongbo, Zhang, Lidong, Dong, Fengqin, Guo, Wei, Wu, Shuhong, Teraishi, Fuminori, Davis, John J., Chiao, Paul J., Fang, Bingliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351116/
https://ncbi.nlm.nih.gov/pubmed/15824729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1208683
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