Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin

Glyceryl trinitrate (GTN), also known as nitroglycerin, has been used to treat angina and heart failure for more than 130 years. Recently, it was shown that mitochondrial aldehyde dehydrogenase-2 (ALDH2) is responsible for formation of NO, the metabolite needed for GTN efficacy. In the present study...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Li, Yifeng, Zhang, Dandan, Jin, Wei, Shao, Chunhong, Yan, Pengrong, Xu, Congjian, Sheng, Haihui, Liu, Yan, Yu, Jinde, Xie, Yuying, Zhao, Yingnan, Lu, Daru, Nebert, Daniel W., Harrison, Donald C., Huang, Wei, Jin, Li
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2006
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351000/
https://ncbi.nlm.nih.gov/pubmed/16440063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26564
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller