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Strong Protective Effect of The Aldehyde Dehydrogenase Gene (ALDH2) 504lys (*2) Allele Against Alcoholism And Alcohol-Induced Medical Diseases in Asians

Alcohol is oxidized to acetaldehyde, which in turn is oxidized to acetate. The aldehyde dehydrogenase 2 gene (ALDH2) is the most important gene responsible for acetaldehyde metabolism. Individuals heterozygous or homozygous for the lys (A or *2) allele at the single nucleotide polymorphism (SNP) glu...

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Detalhes bibliográficos
Main Authors: Li, Dawei, Zhao, Hongyu, Gelernter, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548401/
https://ncbi.nlm.nih.gov/pubmed/22102315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-011-1116-4
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