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ClpXP Protease Regulates the Signal Peptide Cleavage of Secretory Preproteins in Bacillus subtilis with a Mechanism Distinct from That of the Ecs ABC Transporter

Identification and characterization of a suppressor mutation, sup-15, which partially restored secretion in the protein secretion-deficient Bacillus subtilis ecsA26 mutant, led us to discover a novel function of Clp protease. Inactivation of ClpP improved the processing of the precursor of AmyQ α-am...

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Autors principals: Pummi, Tiina, Leskelä, Soile, Wahlström, Eva, Gerth, Ulf, Tjalsma, Harold, Hecker, Michael, Sarvas, Matti, Kontinen, Vesa P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC134792/
https://ncbi.nlm.nih.gov/pubmed/11807061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/jb.184.4.1010-1018.2002
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