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Transduction-Mediated Transfer of Unmarked Deletion and Point Mutations through Use of Counterselectable Suicide Vectors

A challenge in strain construction is that unmarked deletion and nucleotide substitution alleles generally do not confer selectable phenotypes. We describe here a rapid and efficient strategy for transferring such alleles via generalized transduction. The desired allele is first constructed and intr...

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Main Authors: Kang, Ho Young, Dozois, Charles M., Tinge, Steven A., Lee, Tae Ho, Curtiss III, Roy
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC134762/
https://ncbi.nlm.nih.gov/pubmed/11741872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.1.307-312.2002
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