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Mice Lacking the Metalloprotease-Disintegrin MDC9 (ADAM9) Have No Evident Major Abnormalities during Development or Adult Life

MDC9 (ADAM9/meltrin γ) is a widely expressed and catalytically active metalloprotease-disintegrin protein that has been implicated in the ectodomain cleavage of heparin-binding epidermal growth factor-like growth factor (HB-EGF) and as an α secretase for the amyloid precursor protein. In this study,...

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Udgivet i:Mol Cell Biol
Principais autores: Weskamp, Gisela, Cai, Hui, Brodie, Thomas A., Higashyama, Shigeki, Manova, Katia, Ludwig, Thomas, Blobel, Carl P.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11839819/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.22.5.1537-1544.2002
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