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Transforming Growth Factor β1 Induces Apoptosis through Cleavage of BAD in a Smad3-Dependent Mechanism in FaO Hepatoma Cells

Transforming growth factor β (TGF-β) induces apoptosis in a variety of cells. We have previously shown that TGF-β1 rapidly induces apoptosis in the FaO rat hepatoma cell line. We have now studied the effect of TGF-β1 on the expression of different members of the Bcl-2 family in these cells. We obser...

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Detalhes bibliográficos
Main Authors: Kim, Byung-Chul, Mamura, Mizuko, Choi, Kyeong Sook, Calabretta, Bruno, Kim, Seong-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134700/
https://ncbi.nlm.nih.gov/pubmed/11839804
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