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Stable Growth of Wild-Type Hepatitis A Virus in Cell Culture
Human wild-type (wt) hepatitis A virus (HAV), the causative agent of acute hepatitis, barely grows in cell culture and in the process accumulates attenuating and cell culture-adapting mutations. This genetic instability of wt HAV in cell culture is a major roadblock to studying HAV pathogenesis and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346922/ https://ncbi.nlm.nih.gov/pubmed/16415012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1352-1360.2006 |
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