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The interaction of hepatitis A virus (HAV) with soluble forms of its cellular receptor 1 (HAVCR1) share the physiological requirements of infectivity in cell culture

BACKGROUND: Hepatitis A virus (HAV), an atypical Picornaviridae that causes acute hepatitis in humans, usurps the HAV cellular receptor 1 (HAVCR1) to infect cells. HAVCR1 is a class 1 integral membrane glycoprotein that contains two extracellular domains: a virus-binding immunoglobulin-like (IgV) do...

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Detalhes bibliográficos
Main Authors: Silberstein, Erica, Konduru, Krishnamurthy, Kaplan, Gerardo G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775739/
https://ncbi.nlm.nih.gov/pubmed/19860892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-175
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