Pentamidine Is Active in a Neutropenic Murine Model of Acute Invasive Pulmonary Fusariosis

We studied the efficacy of pentamidine (PNT) as prophylaxis or early treatment in acute pulmonary fusariosis in neutropenic mice. PNT-preexposed mice had significantly improved survival and reduced fungal burden compared to amphotericin B-preexposed and untreated mice. PNT-treated mice had increased...

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Главные авторы: Lionakis, Michail S., Chamilos, Georgios, Lewis, Russell E., Wiederhold, Nathan P., Raad, Issam I., Samonis, George, Kontoyiannis, Dimitrios P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2006
Предметы:
Experimental Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346817/
https://ncbi.nlm.nih.gov/pubmed/16377700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.294-297.2006
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