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Different Modes of Action of Naphthyridones in Gram-Positive and Gram-Negative Bacteria

Naphthyridones that were recently described as a class of translation inhibitors in gram-positive bacteria mediate their mode of action via GyrA in Haemophilus influenzae and Escherichia coli. These are the first examples of compounds in which modes of action in different bacterial pathogens are med...

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Detalles Bibliográficos
Main Authors: Buurman, Ed T., Johnson, Kenneth D., Kelly, Roxanne K., MacCormack, Kathy
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346805/
https://ncbi.nlm.nih.gov/pubmed/16377719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.385-387.2006
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