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Different Modes of Action of Naphthyridones in Gram-Positive and Gram-Negative Bacteria

Naphthyridones that were recently described as a class of translation inhibitors in gram-positive bacteria mediate their mode of action via GyrA in Haemophilus influenzae and Escherichia coli. These are the first examples of compounds in which modes of action in different bacterial pathogens are med...

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Bibliografske podrobnosti
Main Authors: Buurman, Ed T., Johnson, Kenneth D., Kelly, Roxanne K., MacCormack, Kathy
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346805/
https://ncbi.nlm.nih.gov/pubmed/16377719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.385-387.2006
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