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Different Modes of Action of Naphthyridones in Gram-Positive and Gram-Negative Bacteria

Naphthyridones that were recently described as a class of translation inhibitors in gram-positive bacteria mediate their mode of action via GyrA in Haemophilus influenzae and Escherichia coli. These are the first examples of compounds in which modes of action in different bacterial pathogens are med...

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Autors principals: Buurman, Ed T., Johnson, Kenneth D., Kelly, Roxanne K., MacCormack, Kathy
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346805/
https://ncbi.nlm.nih.gov/pubmed/16377719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.385-387.2006
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