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Different Modes of Action of Naphthyridones in Gram-Positive and Gram-Negative Bacteria

Naphthyridones that were recently described as a class of translation inhibitors in gram-positive bacteria mediate their mode of action via GyrA in Haemophilus influenzae and Escherichia coli. These are the first examples of compounds in which modes of action in different bacterial pathogens are med...

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Bibliografiska uppgifter
Huvudupphovsmän: Buurman, Ed T., Johnson, Kenneth D., Kelly, Roxanne K., MacCormack, Kathy
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346805/
https://ncbi.nlm.nih.gov/pubmed/16377719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.385-387.2006
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