Utilization of Target-Specific, Hypersensitive Strains of Saccharomyces cerevisiae To Determine the Mode of Action of Antifungal Compounds

Target-specific hypersusceptible strains of Saccharomyces cerevisiae were used to screen antifungal compounds. Two novel Erg7p inhibitors were identified, providing proof of principle of the approach taken. However, observed hypersensitivities to antifungals acting via other targets imply that use o...

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Opis bibliograficzny
Główni autorzy: Buurman, Ed T., Andrews, Beth, Blodgett, April E., Chavda, Jini S., Schnell, Norbert F.
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology 2005
Hasła przedmiotowe:
Mechanisms of Action: Physiological Effects
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140547/
https://ncbi.nlm.nih.gov/pubmed/15917573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.6.2558-2560.2005
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