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IdeS, a Highly Specific Immunoglobulin G (IgG)-Cleaving Enzyme from Streptococcus pyogenes, Is Inhibited by Specific IgG Antibodies Generated during Infection

IdeS, a recently discovered cysteine proteinase secreted by the important human pathogen Streptococcus pyogenes, interferes with phagocytic killing by specifically cleaving the heavy chain of immunoglobulin G. The fact that the enzyme targets one of the key molecules of the adapted immune response r...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Åkesson, Per, Moritz, Linnea, Truedsson, Mikael, Christensson, Bertil, von Pawel-Rammingen, Ulrich
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346671/
https://ncbi.nlm.nih.gov/pubmed/16369006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.497-503.2006
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