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Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG

Pathogenic bacteria have developed complex and diverse virulence mechanisms that weaken or disable the host immune defense system. IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of sub...

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Detalhes bibliográficos
Main Authors: Wenig, Katja, Chatwell, Lorenz, von Pawel-Rammingen, Ulrich, Björck, Lars, Huber, Robert, Sondermann, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC536041/
https://ncbi.nlm.nih.gov/pubmed/15574492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407965101
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