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Adoptive Immunotherapy against Experimental Visceral Leishmaniasis with CD8(+) T Cells Requires the Presence of Cognate Antigen
CD8(+) T cells have a protective role in experimental visceral leishmaniasis. However, the observation that inflammatory cytokines induce bystander activation of CD8(+) T cells questions the need for antigen-dependent effector function. Here, we demonstrate that successful adoptive immunotherapy wit...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346645/ https://ncbi.nlm.nih.gov/pubmed/16369038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.773-776.2006 |
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