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Post-transcriptional regulation of IL-10 gene expression allows NK cells to express immunoregulatory function

NK cells play a well-recognised role in early pathogen containment and in shaping acquired cell-mediated immunity. However, indirect evidence in man and experimental models has suggested that NK cells also play negative regulatory roles during chronic disease. To formally test this hypothesis, we em...

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Détails bibliographiques
Auteurs principaux: Maroof, Asher, Beattie, Lynette, Zubairi, Soombul, Svensson, Mattias, Stager, Simona, Kaye, Paul M.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656759/
https://ncbi.nlm.nih.gov/pubmed/18701085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.06.012
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