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Plasmid Interleukin-23 (IL-23), but Not Plasmid IL-27, Enhances the Protective Efficacy of a DNA Vaccine against Mycobacterium tuberculosis Infection

Protection against intracellular pathogens such as Mycobacterium tuberculosis requires the development of Th1-like T-cell responses. This in turn is dependent on the pattern of cytokine produced from dendritic cells (DCs) after infection. Three heterodimeric cytokines, interleukin-12 (IL-12), IL-23,...

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Autori principali: Wozniak, Teresa M., Ryan, Anthony A., Triccas, James A., Britton, Warwick J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346624/
https://ncbi.nlm.nih.gov/pubmed/16369012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.557-565.2006
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