Secretion of Functional Monocyte Chemotactic Protein 3 by Recombinant Mycobacterium bovis BCG Attenuates Vaccine Virulence and Maintains Protective Efficacy against M. tuberculosis Infection

A strain of Mycobacterium bovis BCG that secretes high levels of functional murine monocyte chemotactic protein 3 (BCG(MCP-3)) was developed. Mice vaccinated with BCG(MCP-3) displayed increased lymphocyte migration in vivo and augmented antigen-specific T-cell responses compared to mice vaccinated w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ryan, Anthony A., Spratt, Joanne M., Britton, Warwick J., Triccas, James A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2007
Gaiak:
Microbial Immunity and Vaccines
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828426/
https://ncbi.nlm.nih.gov/pubmed/17074853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00897-06
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak