Pulmonary Interleukin-23 Gene Delivery Increases Local T-Cell Immunity and Controls Growth of Mycobacterium tuberculosis in the Lungs

Interleukin-23 (IL-23) is a heterodimeric cytokine that shares IL-12 p40 but contains a unique p19 subunit similar to IL-12 p35. Previous studies indicate a greater importance for intact IL-12/23 p40 expression than IL-12 p35 for immunity against Mycobacterium tuberculosis, suggesting a role for IL-...

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Bibliografische gegevens
Hoofdauteurs: Happel, Kyle I., Lockhart, Euan A., Mason, Carol M., Porretta, Elizabeth, Keoshkerian, Elizabeth, Odden, Anthony R., Nelson, Steve, Ramsay, Alistair J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Microbial Immunity and Vaccines
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1231058/
https://ncbi.nlm.nih.gov/pubmed/16113296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.9.5782-5788.2005
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