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Identification of Residues in Yeast Spo11p Critical for Meiotic DNA Double-Strand Break Formation
Saccharomyces cerevisiae Spo11 protein (Spo11p) is thought to generate the DNA double-strand breaks (DSBs) that initiate homologous recombination during meiosis. Spo11p is related to a subunit of archaebacterial topoisomerase VI and appears to cleave DNA through a topoisomerase-like transesterase me...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC134631/ https://ncbi.nlm.nih.gov/pubmed/11809802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.4.1106-1115.2002 |
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