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High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer
Cell surface mannose 6-phosphate/insulin-like growth factor II receptors (M6P/IGF2R) bind and target exogenous insulin-like growth factor II (IGF2) to the prelysosomes where it is degraded. Loss of heterozygosity (LOH) for M6P/IGF2R is found in cancers, with mutational inactivation of the remaining...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1345698/ https://ncbi.nlm.nih.gov/pubmed/16432260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj468 |
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