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Genotype-Epigenotype Interaction at the IGF2 DMR

Paternally expressed Insulin-like Growth Factor II (IGF2) encodes a gene whose protein product functions as a potent growth mitogen. Overexpression of IGF2 has been implicated in a wide number of disorders and diseases. IGF2 is regulated in part by differential methylation of the two parentally deri...

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Détails bibliographiques
Publié dans:Genes (Basel)
Auteurs principaux: Murphy, Susan K., Erginer, Erin, Huang, Zhiqing, Visco, Zachary, Hoyo, Cathrine
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584329/
https://ncbi.nlm.nih.gov/pubmed/26343731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes6030777
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