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CaMKII tethers to L-type Ca(2+) channels, establishing a local and dedicated integrator of Ca(2+) signals for facilitation
Ca(2+)-dependent facilitation (CDF) of voltage-gated calcium current is a powerful mechanism for up-regulation of Ca(2+) influx during repeated membrane depolarization. CDF of L-type Ca(2+) channels (Ca(v)1.2) contributes to the positive force–frequency effect in the heart and is believed to involve...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Rockefeller University Press
2005
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1343528/ https://ncbi.nlm.nih.gov/pubmed/16275756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200505155 |
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